赖氨酸生产装置二级种子罐工艺及设备设计模板

摘 要 赖氨酸发酵过程关键包含斜面种子活化、种子罐扩大培养和发酵罐发酵。种子罐扩大培养在赖氨酸发酵过程中占相关键地位。本设计依据GB150和化工容器和设备简明设计手册等文件，对种子罐进行设计。先行设计种子罐筒体，封头尺寸和厚度并进行液压试验机强度校核。因为反应介质有一定腐蚀性，所以采取不锈钢材料。然后设计设备冷却装置。因为发酵过程中对温度稳定要求高，所以采取外盘管和内蛇管联合使用冷却装置。最终设计设备搅拌传动装置和接管附件。因为发酵过程要求严格无菌操作，对设备密封性能要求高，本设计中采取机械密封。 关键词赖氨酸，种子罐，内蛇管，无菌操作 Abstract Lysine fermentation process mainly includes inclined surface activation of seed, seed tank and enlarged culture fermentation tank fermentation. Seed tank to expand training in lysine fermentation process plays an important role in. In accordance with the design of GB150 and chemical containers and equipment concise design handbook literature, the seed tank design. First design seed tank barrel body, head size and thickness and strength check of hydraulic test machine. As the reaction medium have certain corrosive, so the use of stainless steel materials. Then the design of equipment cooling device. As a result of the fermentation process for the high temperature stability requirements, so taken outside the coil and the inner coil pipe joint use of cooling device. The final design equipment stirring transmission device and attachment of nozzle. Because the fermentation process requires strict aseptic operation, the device sealing perance requirements, the design of the use of mechanical seal. KeywordLysine,seeds cans, inner tube, aseptic operation 目 录 前 言1 第一章 绪论2 1.1赖氨酸用途2 1.1.1赖氨酸在医药上应用2 1.1.2赖氨酸在食品上应用2 1.1.3赖氨酸在饲料上应用2 1.2赖氨酸生产方法2 1.2.1赖氨酸生产方法3 1.2.2二级种子罐在发酵工艺中地位和作用3 第二章 赖氨酸发酵步骤3 2.1赖氨酸发酵原理和过程3 第三章 种子罐釜体结构设计计算4 3.1工艺条件4 3.1.1发酵液物性参数4 3.1.2操作参数4 3.2罐体结构形式选择5 3.2.1筒体内径确实定5 3.2.2筒体全容积确实定6 3.3发酵车间物料衡算6 3.3.1赖氨酸发酵工艺技术指标6 3.3.2种子罐个数确实定7 3.4种子罐罐体设计7 3.4.1工艺条件7 3.4.2筒体壁厚计算8 3.4.3封头壁厚计算9 3.5种子罐水压试验校核10 3.5.1计算罐体水压试验压力10 3.5.2筒体薄膜应力计算10 3.5.3确定筒体在水压试验下最大应力10 3.6种子罐换热部件计算11 3.6.1种子罐内热量衡算11 3.6.2换热装置设计计算13 3.6.3半圆形外盘管强度计算15 3.7挡板设计16 3.8支座选择和强度校核17 3.8.1支座选择17 3.8.2支座强度校核18 3.9人孔、视镜选择和校核20 3.9.1人孔选择和开孔补强20 3.9.2视镜选择和开孔补强24 3.10接管、管法兰设计27 3.10.1放料口